Neosporin Ophthalmic Ointment

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NEE-oh-spor-in oph-THAL-mik OINT-ment - Pronunciation guide

Brand Names

  • Neosporin Ophthalmic Ointment


Rx symbolNeosporin ophthalmic solution is a sterile antibiotic solution composed of neomycin, polymyxin B sulfates, and gramicidin, providing a sterile antimicrobial compound for use in horse's eyes. Used for the topical treatment of superficial infections of the external eye, this combination drug is active against the following microorganisms: Staphylococcus, aureus, streptococci, Escherichia, coli Haemophilus,influenzae, Klebsiells/Enterobacter species, Neisseria species, and Pseudomonas aeruginosa.


Neosporin ophthalmic solution is indicated for the topical treatment of superficial infections, including conjunctivitis, keratitis, keratoconjunctivitis, blephantis, and blepharoconjunctivis.

Dosage and Administration

Prescription medicationNeosporin Ophthalmic Ointment
Method Dosage
(click row for calculator)
Concentration Period Duration
Ocular 2 drops   4 times a day 7 days


  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  • Extra-label use of drugs in treating animals is allowable only by licensed veterinarians within the context of a valid veterinarian-client-patient relationship, and does not include drug use in treating animals by the layman (except under the supervision of a licensed veterinarian).
  • The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your equine appears to feel better, the entire treatment plan should be completed to prevent relapse.
  • This medication may be available in forms and concentrations not noted in the above table. Always check the label and literature provided with the medication about the form and concentration and DO NOT USE the calculator if the information differs.
  • Calculator is for educational purposes only. Follow your veterinarian's instructions regarding use of this, or any medication.

Side Effects

Manifestations of sensitization to Neosporin Ophthalmic Ointment may include itching, reddening, and edema of the conjunctiva or eyelid.


Neosporin Ophthalmic Ointment should never be directly introduced into the anterior chamber of the eye or injected into the eye.

Prolonged use of Neosporin Ophthalmic Ointment may result in overgrowth of nonsusceptible organisms, including fungi.

If purulent discharge, inflammation, or pain becomes aggravated, use of the medication should be discontinued and a veterinarian consulted.


Allergic cross-reactions may occur with the use of the following antibiotics: kanamycin, paromomycin, streptomycin, and possibly gentamicin.


Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi.


Neosporin Ophthalmic OintmentNeosporin Ophthalmic Ointment


About the Author

EquiMed Staff

EquiMed staff writers team up to provide articles that require periodic updates based on evolving methods of equine healthcare. Compendia articles, core healthcare topics and more are written and updated as a group effort. Our review process includes an important veterinarian review, helping to assure the content is consistent with the latest understanding from a medical professional.