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praz-i-KWAN-tel - Pronunciation guide

Brand Names

  • Equimax
  • Zimectrin Gold
  • Quest Plus


Rx symbolPraziquantel is an antiparasitic drug used to control tapeworms (Anoplocephala perfoliata) in horses.


In formulations labeled for use in horses, praziquantel is typically combined with another anthelmintic deworming drug such as ivermectin or moxidectin.

Dosage and Administration

Prescription medicationPraziquantel
Method Dosage
(click row for calculator)
Concentration Period Duration
Oral 1 2.5 mg/kg 7.75% Treatment NA
Oral2 2.5 mg/kg 12.5% Treatment NA


  • For veterinary use only.
  • Not for use in horses intended for food.
  • Calculator is for educational purposes only. Follow your veterinarian's instructions regarding use of this, or any medication.

Side Effects

Neurologic signs were seen in safety studies at 5 times the label dose of the moxidectin/praziquantel mixture (Quest Plus). Some reports of colic after praziquantel administration have occurred in horses that had very high tapeworm loads.  Generally considered safe well past label doses.


Equine dewormers can be toxic to dogs and cats. Clean barn aisles, wash-racks, etc. after administration. Avoid contact with human eyes and mouth. For equine use only.


None noted.


Generally safe in studies at levels up to 3-5 times label dose.  At high doses, toxicity signs as noted above may occur.



Quest Gel MoxidectinQuest Gel Moxidectin


About the Author

EquiMed Staff

EquiMed staff writers team up to provide articles that require periodic updates based on evolving methods of equine healthcare. Compendia articles, core healthcare topics and more are written and updated as a group effort. Our review process includes an important veterinarian review, helping to assure the content is consistent with the latest understanding from a medical professional.