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SOO-kral-fate - Pronunciation guide

Brand Names

  • Carafate


Rx symbolSucralfate is a drug used in the management and prevention of equine gastric ulcers. Its effects are local rather than systemic and it does not affect production of gastric acid.


Since sucralfate provides a protective coating over injured mucosa, or lining of the stomach and small intestine in the horse, it is often prescribed by veterinarians to both prevent and treat gastrointestinal ulcers.

Sucralfate is most effective in treating ulcers affecting the glandular part of the stomach. Since ulcers in foals and adult horses often involve the non-glandular part of the stomach, or the squamous areas, a veterinarian's diagnosis is important. In cases involving the squamous type of mucosa or stomach/intestinal lining, sucralfate may be used in addition to other drugs, such as omeprazole or rantidine.

Dosage and Administration

Prescription medicationSucralfate
Method Dosage
(click row for calculator)
Concentration Period Duration
Oral 20-40 mg/kg 1000 mg/tablet 2 to 4 times daily NA


  • Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  • Extra-label use of drugs in treating animals is allowable only by licensed veterinarians within the context of a valid veterinarian-client-patient relationship, and does not include drug use in treating animals by the layman (except under the supervision of a licensed veterinarian).
  • The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your equine appears to feel better, the entire treatment plan should be completed to prevent relapse.
  • This medication may be available in forms and concentrations not noted in the above table. Always check the label and literature provided with the medication about the form and concentration and DO NOT USE the calculator if the information differs.
  • Calculator is for educational purposes only. Follow your veterinarian's instructions regarding use of this, or any medication.

Side Effects

In some cases, constipation may occur.


Sucralfate is not FDA approved for use with horses, but is commonly used and an accepted practice. It is a prescription drug restricted by U. S. federal law to use by or on the lawful written or oral order of a licensed veterinarian.

Sucralfate is prohibited in any drug-free competition. It is important to check with the individual regulatory group.


Sucralfate can decrease the absorption of many drugs and should not be given within two hours of most other oral medications. Administration at the same time as the H2 antagonists does not appear to interfere with either drug's activity.


Difficulties due to overdose are very unlikely.


Nostrum Sucralfate Tablets USPNostrum Sucralfate Tablets USP

Sucralfate TabletsSucralfate Tablets


About the Author

EquiMed Staff

EquiMed staff writers team up to provide articles that require periodic updates based on evolving methods of equine healthcare. Compendia articles, core healthcare topics and more are written and updated as a group effort. Our review process includes an important veterinarian review, helping to assure the content is consistent with the latest understanding from a medical professional.